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Chris Klay

Southern Illinois Market CEO and President and CEO

HSHS St. Elizabeth’s Hospital

O’Fallon, IL

Mr. Klay oversees four hospitals across the HSHS Southern Illinois market, including three rural facilities, while also serving as CEO of HSHS St. Elizabeth’s Hospital, a 144-bed regional medical center in O’Fallon, Ill. A physical therapist by training, Mr. Klay brings clinical insight to executive decision-making and has spent his entire career with HSHS since 2009, advancing from director of rehabilitation services to market-level leadership. In fall 2025, he announced $116 million in growth projects for the St. Elizabeth’s campus, expanding the emergency department, increasing inpatient nursing capacity, adding an outpatient surgery center and advanced imaging options to serve a rapidly growing community. Under his leadership, HSHS St. Joseph’s Hospital in Breese, Ill. was named a Chartis “Top 100 Rural and Community Hospital” and a “Top 20 Rural and Community Hospital” by the National Rural Health Association in 2025, while multiple Southern Illinois market hospitals earned CMS five-star ratings for quietness, nurse communication and low catheter-associated urinary tract infection rates. Mr. Klay is a fellow of the American College of Healthcare Executives and previously served as president and CEO of HSHS St. Joseph’s Hospital and St. Joseph’s Hospital in Highland, Ill.

Becker's Recognition

Chris Klayhas been named a Becker's honoree on the lists below.

2024 Winner

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2025 Winner

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Community hospitals are often the unsung heroes in healthcare, and CEOs are tasked with managing the delivery of coordinated and affordable community care. Beyond just acute care, many community hospital CEOs also ensure that patients can access primary care, rehabilitation, public health services and other resources. Executives are responsible for fostering a positive workforce culture, overseeing strategy, expanding service lines and maintaining financial stability.

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2026 Winner

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240 Community Hospital CEOs to Know

Community hospitals are often the unsung heroes in healthcare, and CEOs are tasked with managing the delivery of coordinated and affordable community care. Beyond just acute care, many community hospital CEOs also ensure that patients can access primary care, rehabilitation, public health services and other resources. Executives are responsible for fostering a positive workforce culture, overseeing strategy, expanding service lines and maintaining financial stability.

CEO

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