Ms. Lukasick serves as regional CFO for Loyola Medicine and Trinity Health’s west/midwest service area, with financial accountability for acute care, medical group and ambulatory operations spanning Illinois, Indiana, Iowa, South Dakota, California, Idaho and Oregon. She oversees teams responsible for accounting, financial operations, IT, operational excellence, payer strategy, planning, design and construction, real estate, revenue cycle and supply chain across a portfolio generating more than $9 billion in annual revenue. Ms. Lukasick has led multiple financial turnarounds by partnering with clinical and operational leaders to implement cost-saving initiatives, lean management practices and data-driven performance improvement. She spearheaded the creation of a centralized data hub that provides real-time financial and operational metrics, enabling more agile decision-making and supporting the regionalization of administrative shared services while maintaining positive margins despite industrywide pressures. Her leadership was instrumental in Trinity Health’s acquisition of Loyola Medicine, the integration of MacNeal Hospital in Berwyn, Ill. and the development of Loyola Medicine’s $70 million outpatient center in Tinley Park, Ill. Ms. Lukasick also contributes at the system and state levels through roles on Trinity Health’s strategic investment and administrative policy committees and the Illinois Health and Hospital Association finance and audit committee.
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Becker's Recognition
Melissa Lukasickhas been named a Becker's honoree on the lists below.
2024 Winner

Executives
Academic Medical Center CFOs to Know
Academic medical centers bring together quality patient care with innovative research and education. The CFOs responsible for the overall financial health of these institutions lead long- and short-term financial strategies, manage large budgets and oversee strategic partnerships.
CFO
2025 Winner

2025 Winner

Hospital & Health Systems
Women Hospital and Health System CFOs to Know
Female CFOs of hospitals and health systems skillfully handle strategic financial planning, annual budgets, investments and more.
CFO
