States ranked by cancer death rates

In 2021, 32,127 more males died from cancer in the U.S. than females. Males accounted for nearly 53 percent of the 605,213 total cancer deaths across the country, according to data from KFF.

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California had the most cancer deaths that year, with a total of 59,503 — 30,834 males and 28,669 females. Alaska had the least at 1,093.

KFF compiled this data from CDC information as well as cause of death files. It notes that comparisons of death rates between regions should be done using age for the most accurate information.

Here’s how all 50 states and Washington, D.C., compare from most to least cancer deaths in 2021:

  1. California — 59,503
  2. Florida — 46,937
  3. Texas — 42,552
  4. New York — 32,601
  5. Pennsylvania — 27,664
  6. Ohio — 25,077
  7. Illinois — 23,609
  8. Michigan — 21,211
  9. North Carolina — 20,229
  10. Georgia — 18,136
  11. Virginia — 15,724
  12. New Jersey — 15,481
  13. Tennessee — 14,481
  14. Indiana — 13,983
  15. Washington — 13,547
  16. Missouri — 13,153
  17. Arizona — 12,813
  18. Massachusetts — 12,461
  19. Wisconsin — 11,336
  20. South Carolina — 10,593
  21. Maryland — 10,545
  22. Alabama — 10,429
  23. Kentucky — 10,250
  24. Minnesota — 10,178
  25. Louisiana — 9,246
  26. Oregon — 8,596
  27. Oklahoma — 8,368
  28. Colorado — 8,058
  29. Mississippi — 6,617
  30. Connecticut — 6,526
  31. Arkansas — 6,516
  32. Iowa — 6,258
  33. Kansas — 5,455
  34. Nevada — 5,318
  35. West Virginia — 4,820
  36. New Mexico — 3,822
  37. Nebraska — 3,578
  38. Utah — 3,492
  39. Maine — 3,385
  40. Idaho — 3,130
  41. New Hampshire — 2,831
  42. Hawaii — 2,562
  43. Delaware — 2,178
  44. Montana — 2,157
  45. Rhode Island — 2,115
  46. South Dakota — 1,739
  47. Vermont — 1,446
  48. North Dakota — 1,278
  49. Wyoming — 1,151
  50. Alaska — 1,093
  51. Washington, D.C. — 985

View the full data set and gender breakdowns for each state and region, here.

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