States ranked by cancer death rates

In 2021, 32,127 more males died from cancer in the U.S. than females. Males accounted for nearly 53 percent of the 605,213 total cancer deaths across the country, according to data from KFF.

California had the most cancer deaths that year, with a total of 59,503 — 30,834 males and 28,669 females. Alaska had the least at 1,093.

KFF compiled this data from CDC information as well as cause of death files. It notes that comparisons of death rates between regions should be done using age for the most accurate information.

Here's how all 50 states and Washington, D.C., compare from most to least cancer deaths in 2021:

  1. California — 59,503

  2. Florida — 46,937

  3. Texas — 42,552

  4. New York — 32,601

  5. Pennsylvania — 27,664

  6. Ohio — 25,077

  7. Illinois — 23,609

  8. Michigan — 21,211

  9. North Carolina — 20,229

  10. Georgia — 18,136

  11. Virginia — 15,724

  12. New Jersey — 15,481

  13. Tennessee — 14,481

  14. Indiana — 13,983

  15. Washington — 13,547

  16. Missouri — 13,153

  17. Arizona — 12,813

  18. Massachusetts — 12,461

  19. Wisconsin — 11,336

  20. South Carolina — 10,593

  21. Maryland — 10,545

  22. Alabama — 10,429

  23. Kentucky — 10,250

  24. Minnesota — 10,178

  25. Louisiana — 9,246

  26. Oregon — 8,596

  27. Oklahoma — 8,368

  28. Colorado — 8,058

  29. Mississippi — 6,617

  30. Connecticut — 6,526

  31. Arkansas — 6,516

  32. Iowa — 6,258

  33. Kansas — 5,455

  34. Nevada — 5,318

  35. West Virginia — 4,820

  36. New Mexico — 3,822

  37. Nebraska — 3,578

  38. Utah — 3,492

  39. Maine — 3,385

  40. Idaho — 3,130

  41. New Hampshire — 2,831

  42. Hawaii — 2,562

  43. Delaware — 2,178

  44. Montana — 2,157

  45. Rhode Island — 2,115

  46. South Dakota — 1,739

  47. Vermont — 1,446

  48. North Dakota — 1,278

  49. Wyoming — 1,151

  50. Alaska — 1,093

  51. Washington, D.C. — 985

View the full data set and gender breakdowns for each state and region, here.

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