The researchers observed 331 patients who received small doses of the study drug or a placebo. No treatment-related serious adverse effects were reported in either diclofenac dose group, whereas only one was reported in the kerorolac group.
For patients with acute moderate and severe pain after abdominal or pelvic surgery, repeated lower doses of solubilized diclofenac provided significant analgesic efficacy, as compared with the placebo. It significantly reduced the need for opioids.
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