Mount Sinai research may help develop patient-specific cell-replacement therapies

Researchers at the Icahn School of Medicine at Mount Sinai in New York have discovered a precursor cell in the placenta and embryo of mice that can be developed in a lab to create hematopoietic stem/progenitor cells, or blood stem cells.

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The results of the research may help advance patient-specific hematopoietic stem/progenitor cells and produce more individualized blood products for cell-replacement therapy. Should the researchers identify how to program stem cells to the needs of specific patients, they could help treat diseases such as leukemia, lymphomas, multiple myeloma and immune deficiency.

“To cure disease in the long-term, we need to be able to transplant something that can keep producing new blood cells and won’t be rejected by the patient’s body,” said senior author of the study, Kateri Moore, DVM.

This study has gotten Mount Sinai one step closer to that goal. To learn more, click here.

 

 

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