Researchers identified approximately 100 ICU patients with XDR gram-negative bacterial infections — infections resistant to two or more antibiotics — and compared mortality rates with a control group of ICU patients with infections that were resistant to zero or one antibiotics.
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While XDR infections were more likely in immunocompromised patients as well as patients exposed to the antibiotics amikacin, levofloxacin or trimethoprim-sulfamethoxazole, infection with an XDR strain of bacteria was not independently associated with increased mortality among ICU patients.
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