For the study, researchers exposed rats to various bacteriophage combinations and monitored the effects of these bacterial viruses on the gut microbiome. The viral exposure resulted in increases in gut permeability and endotoxins in the blood.
“HMI scientists have shown for the first time that the impact of bacteriophages may result in increased gut permeability, which is associated with diabetes, Alzheimer’s, autism, heart conditions, rheumatoid arthritis and others,” said Adriana Heguy, PhD, a professor of pathology at the New York University School of Medicine and one of the study’s authors. “This could pave the road to further breakthrough research and new discoveries related to the origin of many diseases.”
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