XBB.1.5 prevalence, by region

The omicron subvariant XBB.1.5 is gaining dominance in the U.S., though its prevalence still varies greatly by region. 

The subvariant accounted for 27.6 percent of U.S. COVID-19 cases in the week ending Jan. 7, up from 18.3 percent the week prior, CDC estimates show.

The Northeast has the highest proportion of cases from XBB.1.5 — sitting at more than 70 percent — while states in the Midwest have the lowest at about 5 percent. 

Below is a breakdown of the subvariant's prevalence in each HHS surveillance region as of Jan. 6:

HHS surveillance region 

Prevalence of XBB.1.5

Region 1 

Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island and Vermont

71.6 percent of all COVID-19 cases 

Region 2 

New Jersey, New York, Puerto Rico and the Virgin Islands


Region 3 

Delaware, District of Columbia, Maryland, Pennsylvania, Virginia and West Virginia


Region 4

Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina and Tennessee


Region 5 

Illinois, Indiana, Michigan, Minnesota, Ohio and Wisconsin


Region 6

Arkansas, Louisiana, New Mexico, Oklahoma and Texas


Region 7

Iowa, Kansas, Missouri and Nebraska


Region 8

Colorado, Montana, North Dakota, South Dakota, Utah and Wyoming


Region 9

Arizona, California, Hawaii, Nevada, American Samoa, Commonwealth of the Northern Mariana Islands, Federated States of Micronesia, Guam, Marshall Islands and Republic of Palau


Region 10 

Alaska, Idaho, Oregon and Washington


For more information on XBB.1.5's transmissibility and severity, click here


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