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Experts in healthcare and the pharmaceutical industry have questioned Mark Cuban's ability to puncture high-priced medicines. In a 90-minute fireside chat with one of his critics, Mr. Cuban said his company has "truly changed the game."

Amid continued demand and coverage restrictions around GLP-1s, the prices of Novo Nordisk's Ozempic and Rybelsus have dropped significantly for individuals covered by Medicare and commercial insurance, according to a new report from HHS.

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