So far in April, seven more drugs are in short supply and six are discontinued, according to the FDA and the American Society of Health-System Pharmacists.
Here are the 13 pharmaceutical supply updates in chronological order:
1. Adenosine injections are in shortage after Akorn Operating Co. closed in February, Pfizer discontinued the product and three drugmakers are reporting a strained supply.
2. A calcium acetate oral solution from Fresenius Medical Care North America is discontinued.
3. A chloramphenicol sodium succinate injection is in shortage from Fresenius Kabi USA. The backorder product is expected to return in May.
4. Ethinyl estradiol, and norethindrone acetate and ferrous fumarate tablets from Allergan Sales are discontinued.
5. Metronidazole injections are discontinued from Pfizer Pharmaceuticals and Hospira.
6. Mycophenolic sodium delayed-release tablets are discontinued from Lupin Pharmaceuticals.
7. Amphetamine aspartate, amphetamine sulfate, dextroamphetamine saccharate and dextroamphetamine sulfate tablets are in shortage. High demand pushed the resupply date to April and May, and for drugmakers experiencing a shortage of the drug's active ingredient, the estimated resupply date is in late June.
8. Clonazepam oral tablets are in shortage. Accord Healthcare said the supply issue is because of a manufacturing issue and cannot estimate a resupply date. Teva Pharmaceuticals did not provide a reason for the shortage but said its release dates are in April and May.
9. Propranolol hydrochloride injections are in shortage, and no presentations are available. Fresenius Kabi and Hikma Pharmaceuticals said they could not predict a resupply date.
10. Amobarbital sodium injections are in shortage because Bausch Health is the sole supplier and is in short supply. The company did not provide a release date.
11. One epinastine hydrochloride ophthalmic solution is discontinued from Breckenridge Pharmaceutical.
12. Lidocaine hydrochloride oral topical solutions (Viscous) 2% are in shortage because of Akorn's closure, and Hikma and Wockhardt USA have products on backorder and allocation with no estimated resupply date. There is not enough supply for usual ordering.
13. One albuterol sulfate inhalation aerosol, metered product is discontinued from Sandoz.