The retrospective study looked at 3,340 patients with cardiac surgery and in-hospital outcomes of postoperative mortality, new acute renal failure and perioperative blood transfusion.
Patients who received aprotinin were more often elderly and female. In-hospital mortality was significantly higher in the aprotinin group compared to the TXA group, up 5 percent. The ICU stay was also significantly increased in the aprotinin group, up 8.3 percent.
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