Mayo Clinic posts 8.1% margin as income from current activities nearly doubles

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Rochester, Minn.-based Mayo Clinic recorded an income from current activities of $442 million (8.1% margin) in the third quarter of 2025, up from an income of $232 million (4.8% margin) during the same period last year, according to its Nov. 21 financial report.

Four things to know:

1. Mayo reported operating revenue of $5.2 billion for the three months ended Sept. 30, up from $4.7 billion during the same period last year. Net medical service revenue increased 10.2% year over year to $4.6 billion. This growth was driven by strong outpatient, surgical and hospital volumes and increased service demand.

2. Operating expenses were $5 billion, up from $4.6 billion during the same period in 2024. Supply and service costs grew 8.6% year over year to $1.8 billion, driven by volume increases. Salaries and benefits increased 7.8% year over year to $2.82 billion, accounting for 56.2% of total expenses. 

3. The system reported $249 million in investment returns and contributions available for current activities in the third quarter, up from $177 million during the same period last year. 

4. Mayo Clinic reported a net income of $1.3 billion in the third quarter, up from $839 million during the same period last year. 

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