In addition to the layoffs, UMC will end its outpatient oncology, outpatient pharmacy and some clinic services, according to the report.
Earlier this year, UMC laid off 105 employees and closed four of its urgent care centers, called UMC Quick Care, that had been losing money.
UMC has been struggling financially for more than a decade, according to the Sun. It is the only public hospital in southern Nevada.
More articles on hospital layoffs:
Trumbull Memorial Hospital to cut 47 nursing positions
Parkland Memorial Hospital cuts 20 jobs
Cape Cod Healthcare to cut 8 lab jobs