Dr. Byrne leads enterprise IT and digital strategy for the nation’s third-largest integrated nonprofit health system, encompassing 69 hospitals and more than 1,100 care sites across multiple states. As the CIO during the strategic system combination that created Advocate Health, she guided IT through a period of extraordinary complexity by unifying complex clinical, administrative and infrastructure environments while maintaining uninterrupted patient care and advancing digital and AI-enabled capabilities simultaneously. A signature accomplishment of her tenure is ensuring the stability and security of the technology environment while advancing frameworks such as FAIR-AI, the “Framework for Appropriate Implementation and Review of AI,” which governs how Advocate Health evaluates AI solutions for equity, reliability, transparency and impact before and during deployment. A board-certified physician with experience in clinical practice and health system leadership, Dr. Byrne brings a clinician’s perspective to enterprise IT decision-making. She also serves as a board member of Truveta and Spok.






