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Annette M. Walker

President

City of Hope Orange County

Irvine, CA

Ms. Walker is the driving force behind City of Hope’s $1.5 billion expansion in Orange County, establishing the region’s only dedicated cancer hospital and most advanced comprehensive cancer center. Under her leadership, the institution has delivered highly specialized, research-driven care to patients, bringing cutting-edge treatments like CAR T-cell therapy and cancer-focused clinical trials directly into the community. She successfully launched the Lennar Foundation Cancer Center in 2022 on time and within budget despite pandemic-related challenges, redefining academic cancer care accessibility. Ms. Walker’s nationally recognized strategic innovation includes landmark partnerships and the mentorship of hundreds of rising healthcare professionals. Her transformational efforts have positioned City of Hope Orange County as a national model of integrated, community-anchored oncology excellence.

Becker's Recognition

Annette M. Walkerhas been named a Becker's honoree on the lists below.

2025 Winner

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236 Women Hospital and Health System Presidents and CEOs to Know

The women leading these hospitals and health systems are passionate about care access, equity and diversity, and the overall improvement of healthcare delivery.

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