Mr. Lefteris leads UCI Health, one of California’s largest academic health systems and the only one in Orange County. He oversees a $4 billion enterprise with 1,317 beds, a National Cancer Institute-designated comprehensive cancer center, level 1 adult and level 2 pediatric trauma centers, a regional burn center, four community hospitals and a network of ambulatory centers serving 5.6 million people across Southern California. Under his leadership, UCI Health-Orange has become one of the top 10 academic medical centers in the nation for quality and earned numerous national awards for sustainability and patient care. Since becoming CEO in 2020, Mr. Lefteris has guided a period of historic growth, sustainability and innovation, including the creation of the UCI Health Community Network and the upcoming openings of UCI Health-Irvine (Calif.), the nation’s first all-electric acute care hospital, and the UCI Health Rehabilitation Hospital. Under his leadership, UCI Health has expanded access to academic medicine, advanced telehealth and home-based preventive care, and become a national model in sustainability. Mr. Lefteris expanded UCI Health’s reach through innovative programs such as “UCI Health OnCall” and partnerships delivering in-home preventive care. A forward-thinking leader recognized by the Orange County Business Journal and Los Angeles Times for his transformative vision, he serves on the boards of Hospital Association of Southern California, America’s Essential Hospitals and Appalachian State University College of Health Sciences advisory board.
