Dr. Sharieff holds leadership over acute care operations, quality, inpatient metrics, information services, pharmacy, inpatient imaging, engineering, environmental services, food and nutrition, security and disaster and emergency management across Scripps Health’s five hospital campuses. She introduced “Sprint Teams,” which are multidisciplinary groups drawn from across Scripps’ five hospitals that focus on a single safety or quality challenge and implement changes within a year, thus producing significant reductions in infection rates and patient falls across the system. Under this model, surgical site infections decreased 67% overall with a 50% reduction in colon-related surgical infections, central line infections declined 37%, catheter-related urinary tract infections fell 20% and patient falls with injury decreased substantially across emergency departments, urgent care locations, medical-surgical units and ambulatory clinics. Dr. Sharieff also developed the “6 Rs” framework to communicate Scripps’ key organizational objectives to staff, contributing to a 3.2% decrease in average patient length of stay. She oversees Scripps’ opioid stewardship program, which was recognized in 2025 with all Scripps hospitals named to Cal Hospital Compare’s “Opioid Care Honor Roll” for reducing high-dose opioids at discharge and expanding alternative pain management options. In 2025, multiple Scripps hospitals earned “A” safety grades from The Leapfrog Group.
