Dr. Brennan oversees healthcare quality, patient safety, regulatory affairs and medical affairs across Penn Medicine’s seven hospitals and extensive outpatient network, which delivers millions of outpatient, emergency and home health visits annually. An expert in infectious diseases, he has served as chair of the Healthcare Infection Control Practices advisory committee, advising national health leaders on disease prevention and control. Dr. Brennan’s leadership extends to public health through his role on the inaugural board of health for the Delaware County Health Department and his appointment as official host city medical lead for “FIFA World Cup 26 Philadelphia”. His career has included leadership positions at the Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center and the Philadelphia VA Medical Center, where he advanced infection control and quality improvement initiatives. Under his guidance, Penn Medicine continues to achieve national recognition for its pioneering research, including CAR T cell therapy and Nobel Prize-winning mRNA vaccine technology.
