Ms. St. John brings strategic vision, operational discipline and patient-centered leadership in healthcare cybersecurity to her role at CHOP, a $5.2-billion-a-year pediatric health system and research institute with a workforce of more than 31,000. She has repositioned security as a core safety behavior and business enabler by partnering with executive, clinical and operational leaders to connect cyber judgement to enterprise safety and shared accountability. This is accomplished by embedding three strategic pillars into the program strategy: safeguarding assets, modernizing the program and enabling responsible innovation. Under Ms. St. John’s leadership, the cybersecurity program applies measurable discipline through tabletop events and phishing exercises that strengthen organizational readiness and resilience. From 2022 to 2026, susceptibility improved by 84% and resiliency improved by 169%, showing strength and improvement in CHOP’s safety culture and ability to protect patient care. Her leadership has positioned security as a business enabler, advancing practical, risk-based solutions that protect the enterprise while supporting innovation and operational growth. The program has also demonstrated strong financial stewardship by balancing operational demands while leading response efforts that mitigated millions of dollars in potential financial impact. Beyond the system, Ms. St. John serves on local nonprofit boards and advisory committees, sharing knowledge and supporting organizations that strengthen the broader community.
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Becker's Recognition
Monique St. Johnhas been named a Becker's honoree on the lists below.
2025 Winner

Executives
Hospital and Health System CISOs and CPOs to know
CIO & IT Executive
2026 Winner

Executives
55 Hospital and Health System CISOs and Chief Privacy Officers to Know
