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Steve Mackin

President and CEO

Mercy

Chesterfield, MO

Mr. Mackin leads Mercy, overseeing 55 hospitals, more than 1,000 physician practices and clinics, and more than 50,000 co-workers. A national leader in the integration of AI into healthcare delivery, he led Mercy’s partnership with Mayo Clinic, aiming to create a global healthcare database that will identify and treat diseases earlier, and forged a partnership with Microsoft to integrate AI into patient care environments. Recent milestones include selection as one of only 10 study sites nationwide to test an AI sepsis detection tool and recognition as one of only four health systems in the nation to receive the 2025 KLAS “Arch Collaborative EHR Breakthrough Recognition” for using AI to improve patient care and clinician satisfaction. Additional innovations under his leadership include AI integration into imaging services, autonomous hospital logistics robots, ambient and generative AI tools in clinical practice, and a hospital care at home program. Mr. Mackin also oversaw the development of the “Mercy Works On Demand” app, used by 24,000 employees. The app gives nurses greater flexibility in scheduling shifts and hours, driving meaningful improvements in recruitment, retention and labor spend. Beyond clinical innovation, Mercy’s ACO ranks in the top five nationally for patients served and generated $102 million in taxpayer savings, with quality ranking third among similarly sized ACOs. Mr. Mackin chairs the American Hospital Association’s Committee on Health Care Strategy and Innovation, serves on the boards of the Heartland Whole Health Institute and the St. Louis Symphony Orchestra, and is a member of the executive committee of the Chair’s Council of Greater St. Louis.

Becker's Recognition

Steve Mackinhas been named a Becker's honoree on the lists below.

2026 Winner

Great Leaders in Healthcare

Healthcare is rapidly evolving and the best leaders have embraced change and are leading organizations on the forefront of transforming care delivery. The below leaders are using innovative digital technology, novel care delivery approaches and creative care solutions to shape the future of healthcare.

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