Dr. Stein is chief clinical innovation officer at Hartford HealthCare, where he has spent two decades translating opportunities at the intersection of care delivery and transformative technology into scalable clinical and operational impact. He has built a multi-stakeholder innovation ecosystem spanning academic institutions, government and corporate partners, venture capital and collaborations with MIT to accelerate ideas from research into bedside practice. In 2024, Dr. Stein and colleagues launched a center for AI innovation in healthcare to advance AI use in a safe and trustworthy manner across access, affordability, equity, quality and safety priorities. The system undertook a nine-plus-year foundation-building effort that includes governance to reduce patient harm risk, immersive education across functions and a disciplined methodology to integrate and scale AI into clinical practice. Dr. Stein also co-founded Holistic Hospital Optimization in 2022 with MIT Sloan collaborators to develop practice models that improve length of stay and optimize complex nursing schedules. More than 200 Hartford HealthCare clinicians and operational leaders are engaged alongside 20-plus PhD students and faculty from institutions including MIT and Oxford University to advance research, startup partnerships and a multimodal data liquidity layer.



