In January 2024, Ms. Gresham became CEO of Pennsylvania Hospital, the nation’s oldest hospital and a vital part of Penn Medicine, bringing with her nearly 30 years of healthcare leadership experience. At Pennsylvania Hospital, she oversees a Magnet-designated academic institution known for clinical excellence in cardiology, neurosciences, behavioral health and women’s health. Ms. Gresham brings strong financial acumen, systems integration expertise and a passion for community health to her role. She previously served as senior vice president and COO of network operations at New York City-based Mount Sinai Health System, where she expanded ambulatory services across multiple states and led initiatives to improve access, unify systems and increase revenue. Earlier in her career, Ms. Gresham held operational leadership roles at Penn Medicine and the Children’s Hospital of Philadelphia.






