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Lori Knowles

Senior Vice President and CHRO

Memorial Hermann Health System

Houston, TX

Ms. Knowles serves as Memorial Hermann’s top human resources executive and a strategic thought partner to the executive leadership team as the system advances a value-focused care delivery model. She designed and leads the “Well Together Human Capital Strategy,” differentiating Memorial Hermann through culture and employee experience, structured talent pathways, educational partnerships and skills-based career tracks, while also serving as executive liaison to the board’s compensation committee. Her recent results include reducing contract labor reliance by 95% from fiscal year 2022 to fiscal year 2026 and decreasing total turnover by 37% over fiscal year 2021 to fiscal year 2026, including a 43% reduction in first-year turnover. Ms. Knowles increased internal mobility to 37%, with approximately 30% of moves being promotions and 64% of executive hires filled internally, while strengthening pipeline readiness to offset leadership continuity risk as 26% of leaders are over the age of 55. She oversees benefits supporting more than 49,000 covered lives and $400 million-plus in health plan spend, including health plan optimization that reduced unnecessary utilization and delivered approximately $9 million in annual GLP-1-related savings. She also launched a system maternity experience program in October 2025, with 65% of enrolled employees engaging a nurse navigator and 92% using the associated app. Her leadership has been recognized with HRO Today’s 2025 “CHRO of the Year” award for the North American nonprofit category.

Becker's Recognition

Lori Knowleshas been named a Becker's honoree on the lists below.

2026 Winner

Executives

140 Hospital and Health System CHROs and Chief People Officers to Know

Chief human resources officers and chief people officers are tasked with developing strong human capital strategies for their hospitals and health systems.

These leaders have a wide range of responsibilities, including oversight of recruitment, retention, compensation, benefits, development and much more. As top human resources executives, their efforts are crucial in shaping workforce culture in alignment with their organization’s values.

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