Mr. Nazarian leads City of Hope’s enterprisewide technology vision, transforming and expanding digital, AI, and advanced analytics capabilities to support an expanding national cancer network and accelerate progress across diagnosis, treatment and research. A defining accomplishment under his leadership is the development and deployment of “HopeLLM,” a proprietary generative AI platform built by multidisciplinary digital, clinical and data science teams to responsibly leverage City of Hope’s extensive oncology data. The platform generates clinician-ready summaries for referred and new patients, dramatically reducing time spent reviewing hundreds of pages of records and flagging potential care friction such as missing documentation or inconsistencies that could delay scheduling. The platform has also been embedded into research and trial operations, supporting feasibility assessments for more than 200 clinical trials across City of Hope’s national system and compressing processes that once took weeks into minutes, enabling studies to open across multiple locations nearly simultaneously and expanding patient access to leading-edge therapies. Mr. Nazarian’s approach places a rigorous emphasis on responsible AI implementation, with HopeLLM built around human-in-the-loop clinical oversight, clear sourcing and citations, regulatory controls and continuous monitoring. Mr. Nazarian brings more than 25 years of experience across healthcare delivery, consulting and payer organizations, including roles at Optum Health, McKinsey & Company, Oakland, Calif.-based Kaiser Permanente and Sony Pictures Entertainment.
