Dr. Spellberg serves as chief medical officer at LA General Medical Center, with dual reporting to the hospital CEO and the health system chief medical officer. He is responsible for providing enterprisewide clinical, operational and physician leadership oversight. He directly oversees 19 chief physicians responsible for more than 1,500 credentialed physicians, the designated institutional official overseeing more than 1,000 residents and fellows, and the departments of risk management, pharmacy and the medical staff office. His tasks include setting clinical strategy, advancing quality and safety, ensuring regulatory and accreditation compliance, and leading workforce recruitment, transitions and succession planning. The system has seen measurable transformation under his leadership, including an improved Leapfrog safety grade that went from “D” to “A,” reducing the mortality index from 1.3 to 0.7, decreasing the length-of-stay index from 1.35 to about 1.00, and increasing case mix index from 1.4 to over 1.7. He oversaw the hiring of more than 270 physicians and allied health professionals during a major staffing transition and restructured physician leadership roles to strengthen accountability and performance. He also led innovations including “Safer@Home” and the nation’s first transitional hemodialysis unit, alongside enterprise infection reduction work and executive leadership of the hospital’s Covid-19 response. In addition, he is the co-founder and CEO of WikiGuidelines, and his work includes national editorial and advisory roles in infectious diseases and antimicrobial stewardship.


