Mr. McCallister oversees UPMC’s IT division, leading more than 2,800 IT professionals in the delivery of centralized technology services supporting clinical care, insurance services, research and international operations across more than 40 hospitals and 800 outpatient sites. With more than 35 years in IT and over 25 years at UPMC, he is responsible for enterprise technology strategy, delivery and infrastructure, with a focus on performance, reliability, security and efficiency at scale. Under his leadership, the IT division manages more than 530,000 connected devices, 3,900-plus applications, 200,000-plus medical devices and more than 29,000 databases. A major recent milestone has been leading the wave 1 go-live of the “UPMC Bridges” initiative, a multi-year effort to consolidate nine primary EHRs and numerous applications into a unified Epic-powered record to reduce fragmentation and streamline workflows. He has advanced AI adoption through ambient documentation support and additional AI-enabled capabilities tied to the unified EHR, while also driving large-scale infrastructure modernization to support go-lives and strengthen claims processing and member engagement for UPMC’s insurance businesses. Mr. McCallister has continued to mature cybersecurity incident response, risk management and identity and network security, contributing to UPMC’s fourth consecutive biennial “HITRUST r2” IT infrastructure certification. He is also the founder and executive sponsor of UPMC’s employee resource group for women in IT, and leads mentorship and engagement programs that strengthen culture and talent development.
Becker's Recognition
Edward McCallisterhas been named a Becker's honoree on the lists below.
2023 Winner

2024 Winner

Executives
CIOs of Hospitals and Health Systems to Know
Chief information officers utilize new and innovative technologies to optimize, streamline and improve healthcare delivery. The featured IT executives are leading strategic initiatives that benefit patients and providers. In collaboration with their talented teams, they are modernizing their hospitals and health systems by implementing new EHR systems, cybersecurity softwares and telehealth services.
2025 Winner

2026 Winner

Executives
135 Hospital and Health System CIOs to Know
Chief information officers utilize new and innovative technologies to optimize, streamline and improve healthcare delivery. The featured IT executives are leading strategic initiatives that benefit patients and providers. In collaboration with their talented teams, they are modernizing their hospitals and health systems by implementing new EHR systems, cybersecurity softwares and telehealth services.
