Single Antibiotic Could Increase Risk of C. Difficile, Study Shows

Results from a recent study showed that administration of a single antibiotic increased mice's susceptibility to C. difficile, according to research published in Infection and Immunity.

 

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For their study, researchers from Memorial Sloan-Kettering Cancer Center in New York City administered a single dose of clindamycin to a group of mice. Results showed the mice experienced weight loss, diarrhea and colitis and a 40-50 percent higher mortality rate. In addition, surviving mice remained susceptible to C. difficile infection for at least 28 days.

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Two California Hospitals Report C. Diff Outbreaks

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