Several classes of antibiotics may up miscarriage risk, study shows

Numerous classes of antibiotics were associated with an uptick in risk of miscarriages, according to a study published in Canadian Medical Association Journal. These classes of common antibiotics include macrolides, quinolones, tetracyclines, sulfonamides and metronidazole.

Researchers examined 8,702 cases, defined as clinically detected spontaneous abortions. They matched the cases with 87,020 control cases. The miscarriage occurred at 14 weeks of pregnancy.

Sign up for our FREE E-Weekly for more coverage like this sent to your inbox!

The study shows that 1,428 (16.4 percent), of the miscarriage cases were exposed to antibiotics during early pregnancy, as compared to 11,018 (12.6 percent) among the control cases. However, erythromycin and nitrofurantoin (a common treatment for urinary tract infections in pregnant women) were not associated with increased risk.

"Infections are prevalent during pregnancy," said Dr. Anick Bérard, of the Université de Montréal in Canada and a study author. "Although antibiotic use to treat infections has been linked to a decreased risk of prematurely and low birth weight in other studies, our investigation shows that certain types of antibiotics are increasing the risk of spontaneous abortion, with a 60 percent to two-fold increased risk."

More articles on healthcare quality:
Leapfrog: Hospitals aren't using medication safety technology effectively
Follow-up colonoscopies can significantly reduce colorectal cancer in certain high-risk patients, study finds
Minnesota measles outbreak jumps to 29 cases

© Copyright ASC COMMUNICATIONS 2019. Interested in LINKING to or REPRINTING this content? View our policies by clicking here.

 


IC Database-3

Top 40 Articles from the Past 6 Months