Mayo Clinic awarded $13.3M grant to test breast cancer vaccine

Researchers at the Jacksonville, Fla., campus of Rochester, Minn.-based Mayo Clinic have been awarded a $13.3 million, five-year federal grant to test a vaccine that aims to prevent the recurrence of triple-negative breast cancer.

The grant is funded through the U.S. Department of Defense's Breast Cancer Research Program and Breakthrough Award. It will fund the second phase of Mayo's clinical trial, which will enroll 280 patients across the country and test the ability of a folate receptor alpha vaccine to prevent recurrence of triple-negative breast cancer following initial treatment.

The folate receptor alpha vaccine was designed by the grant's principal investigator, Keith Knutson, PhD, and was initially tested by researchers at Mayo Clinic's Rochester campus for safety and efficacy.

The newly funded trial is scheduled to begin in early 2016.



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