Researchers performed whole genome sequencing on C. diff isolates collected from children diagnosed with C. diff between December 2012 and December 2013 at a single academic medical center. In all, they studied 104 genetically distinct isolates collected from 131 C. diff infections in 107 children.
Researchers compared genome sequences of isolates from C. diff infections diagnosed at eight weeks or more after the study initiation to all study isolate genome sequences.
They found that of 84 incident C. diff infections occurring at eight weeks or more after study initiation, only 11.9 percent were caused by a strain with genotype similar to another cohort C. diff infection isolate.
Researchers also found transmission events among different classes of C. diff infections — hospital-onset healthcare facility-associated, community-onset healthcare facility-associated, indeterminate, community-associated and recurrent — were uncommon. Transmission events among community-associated and healthcare facility-associated C. diff infections were also found to be infrequent.
More articles on healthcare quality:
VA sees 36% drop in C. diff infections at long-term care facilities over 2 years
CDC chief: 85% of children who’ve died this flu season were unvaccinated
DMC Children’s Hospital brings sterile processing in-house
At the Becker's 11th Annual IT + Revenue Cycle Conference: The Future of AI & Digital Health, taking place September 14–17 in Chicago, healthcare executives and digital leaders from across the country will come together to explore how AI, interoperability, cybersecurity, and revenue cycle innovation are transforming care delivery, strengthening financial performance, and driving the next era of digital health. Apply for complimentary registration now.
