Researchers contacted 190 eligible patients who received FMT for recurrent Clostridium difficile infection for a follow-up survey. Of the 190 patients, 137 completed the survey. The median time from last FMT to follow-up was 22 months.
Eighty-two percent of patients at follow-up had experienced no recurrence of C. diff post-FMT (non-RCDI group) and 18 percent of patients had C. diff post-FMT (RCDI group). Antibiotic exposure for non-C. diff infections after FMT was more common in the RCDI group as compared to the non-RCDI group.
Eleven percent of patients reported improvement or resolution of diagnoses not related to C. diff post-FMT while 33 percent reported development of a new medical condition or symptom post-FMT.
Additionally, 95 percent of patients indicated they would undergo FMT again; of which, 70 percent reported they would prefer FMT to antibiotics as initial treatment if they were to experience recurrent C. diff.
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