Cancer cells have a different level of acidity than healthy cells, causing them to react differently to pH-sensitive dye that changes color based on a cell’s acidity.
Researchers then used machine learning to map color combinations to classify the disease state of individual cells. This allowed researchers to recognize an undesired shift.
Other popular techniques for examining a single cell can be invasive and induce toxic effects on the cell. This method does not do either, the report says.