A study, published in Clinical Infectious Diseases, shows infants whose mothers receive influenza vaccination during pregnancy are less likely to be hospitalized for acute respiratory tract infection during the first three months of life.
For the study, researchers examined infants born to women who participated in a double-blind placebo-controlled randomized clinical trial in 2011 and 2012. The researchers studied 1,026 infants born to women who received trivalent inactivated influenza vaccine and 1,023 infants born to women who received a placebo.
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Researchers found the incidence (per 1,000 infant-months) of acute respiratory tract infection hospitalizations was lower in infants born to women in the vaccine group compared to the placebo group — 19 cases versus 33 cases. During the first three months of life, there were 30 acute respiratory tract infection hospitalizations among the infants. Of these, nine were born to women in the vaccine group and 21 were women to the placebo recipients.
After the first three months of life, acute respiratory tract infection incidence was similar between the two groups.
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