20 most expensive drugs in the US in 2019

This year, Horizon Pharma's osteopetrosis drug Actimmune tops GoodRx's list of the 20 most expensive drugs in the U.S., with a list price of $52,322 per month.

To create the list, GoodRx excluded drugs that are administered by a healthcare provider and obtained typical fill quantities using drug manufacturer websites to compare the monthly price of these drugs. Using the official manufacturer list price, GoodRx calculated the one-month supply of a typical fill quantity.

GoodRx is an online drug pricing comparison platform.

The 20 most expensive drugs with their monthly list price:

1. Actimmune — $52,322  (Horizon Pharma)

2. Myalept  — $46,329 (Aegerion Pharmaceuticals)

3. Daraprim  — $45,000 (Vyera Pharmaceuticals)

4. Cinryze  — $44,141 (Shire)

5. Takhzyro  — $44,140 (Shire)

6. Chenodal  — $42,570 (Retrophin)

7. Juxtapid  — $40,671 (Aegerion Pharmaceuticals)

8. H.P. Acthar  — $38,892 (Mallinckrodt Pharmaceuticals)

9. Tegsedi  — $34,600 (Akcea Therapeutics)

10. Ravicti  — $33,572 (Horizon Pharma)

11. Vitrakvi  — $32,800 (Bayer and Loxo Oncology)

12. Firazyr  — $32,468 (Shire)

13. Cuprimine  — $31,426 (Valeant Pharmaceuticals)

14. Sovaldi  — $28,000 (Gilead)

15. Viekira Pak  — $27,773 (AbbVie)

16. Viekira XR  — $27,773 (AbbVie)

17. Orfadin  — $27,247 (Apotek Produktion and Laboratorier AB)

18. Tibsovo  — $26,115 (Agios Pharmaceuticals)

19. Cerdelga  — $26,000 (Sanofi Genzyme)

20. Remodulin  — $25,466 (United Therapeutics)

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