There are 37 health systems and medical centers that Optum may refer its payer and employer clients to for complex oncology care.
Optum’s Centers of Excellence networks recognize providers that are clinically superior and offer cost-effective care for cancer, bariatric surgery, congenital heart disease, infertility, and transplants.
The company conducts an annual evaluation process alongside a national panel of industry experts to assess providers across the country, which offers patients a wide range of benefits, including more accurate diagnoses, higher survival rates, and lower out-of-pocket costs. More than 3,000 payer groups covering more than 62 million lives use Optum’s services. Additional evaluation information is here.
The 37 health systems Optum recommends for complex cancer care in 2025:
Alabama
O’Neal Comprehensive Cancer Center at UAB (Birmingham)
Arizona
Mayo Clinic Arizona (Scottsdale)
California
City of Hope Cancer Center (Duarte)
Lucile Packard Children’s Hospital at Stanford (Palo Alto)
Stanford Hospital and Clinics
UC Irvine Medical Center (Orange)
UC San Francisco Helen Diller Family Comprehensive Cancer Center
UC San Diego Medical Center
Colorado
Children’s Hospital Colorado (Denver)
University of Colorado Hospital (Aurora)
Florida
H. Lee Moffitt Cancer Center (Tampa)
Mayo Clinic Florida (Jacksonville)
Illinois
Ann & Robert H. Lurie Children’s Hospital of Chicago
Robert H. Lurie Comprehensive Cancer Center of Northwestern University (Chicago)
Maryland
Sidney Kimmel Comprehensive Cancer Center (Baltimore)
University of Maryland Medical Center (Baltimore)
Massachusetts
Boston Children’s Hospital
Brigham and Women’s Cancer Center (Boston)
Dana-Farber Cancer Institute (Boston)
Massachusetts General Hospital Cancer Center (Boston)
Michigan
Karmanos Cancer Institute (Detroit)
Minnesota
M Health Fairview (Minneapolis)
Mayo Clinic (Rochester)
Nebraska
Fred & Pamela Buffett Cancer Center (Omaha)
New York
Memorial Sloan-Kettering Cancer Center (New York)
Roswell Park Cancer Institute (Buffalo)
Ohio
The Ohio State University Comprehensive Cancer Center (Columbus)
The Cleveland Clinic Foundation
Pennsylvania
Abramson Cancer Center (Philadelphia)
Children’s Hospital of Philadelphia
Sidney Kimmel Cancer Center (Philadelphia)
Tennessee
St. Jude Children’s Research Hospital (Memphis)
Vanderbilt-Ingram Cancer Center (Nashville)
Texas
MD Anderson Cancer Center (Houston)
University Health (San Antonio)
Utah
Huntsman Cancer Institute, University of Utah (Salt Lake City)
Wisconsin
UW Health Carbone Cancer Center (Madison)
