CT scan cuts need for invasive angiography in half: 4 study notes

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Pretranscatheter aortic valve replacement-CT angiography safely deferred the need for invasive coronary angiography in 53% of patients, according to a study published May 21 in Circulation: Cardiovascular Interventions.

Led by researchers from the Minneapolis Heart Institute Foundation, the study analyzed data from 1,165 patients who underwent pretranscatheter aortic valve replacement-CT angiography and invasive coronary angiography to rule out obstructive coronary artery disease between 2017 and 2022.

Here are four notes on the findings:

  1. Of the 1,165 patients, 464 underwent preTAVR-CTA and 701 underwent ICA. Both groups had similar prevalence of obstructive coronary artery disease.

  2. Fifty-three percent of patients were exempted from further ICA after preTAVR-CTA due to the absence of obstructive coronary artery disease, 17% had inconclusive preTAVR-CTA interpretation, 15% requested ICA despite coronary artery disease exclusion by preTAVR-CTA, and 14% had obstructive coronary artery disease requiring further ICA.

  3. Revascularization, acute coronary syndrome and unplanned ICA one year after transcatheter aortic valve replacement were all low and not different between patients who underwent preTAVR-CTA versus ICA.

  4. “This approach could have important clinical implications to improve patient access, experience, value and throughput,” the study authors wrote. 

Read the full study here

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